Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875024 | 1.00 | GAA (0.47) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL9875022 | 1.00 | GAA (0.47) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL9487122 | 0.90 | ALDH1A1 (0.49) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL9487132 | 0.90 | ALDH1A1 (0.49) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL9487135 | 0.90 | ALDH1A1 (0.49) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL9487912 | 0.85 | TDP1 (0.65) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL29918292 | 0.82 | TDP1 (0.42) | GAAALDH1A1MAPTTDP1MAPK8 | |
| SCHEMBL29470271 | 0.81 | HPGD (0.43) | GAAALDH1A1MAPTTDP1MAPK8 | |
| SCHEMBL10517647 | 0.81 | TDP1 (0.50) | GAAALDH1A1MAPTTDP1HTT | |
| SCHEMBL10517652 | 0.81 | TDP1 (0.50) | GAAALDH1A1MAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008276-A | Plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-16 | — | — | US | disclosed |