Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL987591 | 0.89 | TP53 (0.38) | TP53TDP1TRPA1ALDH1A1 | |
| Bromide SCHEMBL986860 | 0.89 | TP53 (0.38) | TP53TDP1TRPA1ALDH1A1 | |
| SCHEMBL29061760 | 0.76 | ALDH1A1 (0.42) | TDP1PTGS2TSHRALDH1A1 | |
| SCHEMBL1204171 | 0.76 | TP53 (0.42) | CYP2C19TP53TDP1TRPA1PTGS2 | |
| SCHEMBL28280668 | 0.73 | TP53 (0.39) | TP53TDP1TRPA1PTGS2ALDH1A1 | |
| SCHEMBL15496943 | 0.71 | AR (0.41) | TP53TDP1TRPA1PTGS2ALDH1A1 | |
| Acetic Acid SCHEMBL1047016 | 0.71 | HPGD (0.40) | CYP2C19TDP1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL940632 | 0.69 | MCL1 (0.48) | TP53TDP1TRPA1RARBCYP1A2 | |
| SCHEMBL12653960 | 0.69 | TDP1 (0.39) | TP53TDP1TRPA1MCL1ESR1 | |
| SCHEMBL15499223 | 0.69 | SMN1; SMN2 (0.41) | TP53TDP1TRPA1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703239-B2 | Image forming method | FUJIFILM CORPORATION (JP) | 2014-04-22 | — | — | US | disclosed |
| EP-1866166-B1 | INK SET FOR INK JET RECORDING, INK FOR INK JET RECORDING, AND INK JET IMAGE RECORDING METHOD | FUJIFILM CORP (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-8220911-B2 | Inkjet recording method | FUJIFILM CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-8187675-B2 | Image forming method | FUJIFILM CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8038254-B2 | Ink set and image forming method | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7984983-B2 | Inkjet recording method | FUJIFILM CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-7906186-B2 | Ink jet recording medium | FUJIFILM CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7866807-B2 | Ink set for ink jet recording, ink for ink jet recording, and ink jet image recording method | FUJIFILM CORPORATION (JP) | 2011-01-11 | — | — | US | disclosed |
| US-7857407-B2 | Image forming apparatus | FUJIFILM CORPORATION (JP) | 2010-12-28 | — | — | US | disclosed |
| US-7753462-B2 | Image forming apparatus | FUJIFILM CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20040241347-A1 | Recording medium | FUJI PHOTO FILM CO., LTD. | 2004-12-02 | — | — | US | disclosed |
| EP-1481812-A2 | Recording medium | FUJI PHOTO FILM CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040167025-A1 | Information medium | FUJI PHOTO FILM CO., LTD. | 2004-08-26 | — | — | US | disclosed |
| US-20040166252-A1 | Ink jet recording medium and ink jet recording method | FUJI PHOTO FILM CO., LTD. | 2004-08-26 | — | — | US | disclosed |
| EP-1450359-A2 | Information medium | FUJI PHOTO FILM CO., LTD. (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-1426194-A2 | Ink jet recording medium and ink jet recording method | FUJI PHOTO FILM CO., LTD. (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-20040101640-A1 | Ink jet recording sheet | FUJI PHOTO FILM CO., LTD. | 2004-05-27 | — | — | US | disclosed |
| EP-1422071-A1 | Ink jet recording sheet | Fuji Photo Film Co., Ltd. (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-20030198885-A1 | Recording material support, process for manufacturing the same, recording material and process for image formation | FUJI PHOTO FILM CO., LTD. | 2003-10-23 | — | — | US | disclosed |
| EP-1325815-A2 | Ink-jet recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2003-07-09 | — | — | EP | disclosed |