SCHEMBL9875151

SCHEMBL9875151

Cc1c(CC(C)C)c(CC(C)C)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.37
MEN1 O00255 4/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
KMT2A Q03164 4/20 0.37
GFER P55789 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
DHODH Q02127 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
CRHBP P24387 2/20 0.34
HTT P42858 2/20 0.34
CRHR2 Q13324 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 2/20 0.34
GAA P10253 1/20 0.34
ADRB3 P13945 2/20 0.34
PTGS1 P23219 2/20 0.33
PTGS2 P35354 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13518830 0.87 LMNA (0.37) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL14989311 0.87 AKR1C2 (0.38) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL14989288 0.83 AKR1C2 (0.38) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL29049604 0.79 AKR1C2 (0.42) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL9875150 0.77 AKR1C2 (0.38) LMNAALDH1A1HPGDAKR1C2AKR1C1
SCHEMBL14989289 0.76 AKR1C2 (0.40) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL3821056 0.76 GABRP (0.39) MEN1KMT2AGABRA1GABRB2SMN1; SMN2
SCHEMBL14989241 0.75 PTGS1 (0.43) LMNAALDH1A1AKR1C2AKR1C1DHODH
SCHEMBL6443243 0.73 LMNA (0.39) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL77326 0.73 LMNA (0.39) LMNAMEN1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245639-B1 PROCESS FOR THE PREPARATION OF UV-HARDENABLE PIGMENTED COATINGS BAYER AG (DE) 1991-06-19 EP disclosed
EP-0245639-A2 Process for the preparation of UV-hardenable pigmented coatings BAYER AG (DE) 1987-11-19 EP disclosed
EP-0056155-B1 AQUEOUS DISPERSIONS CONTAINING NITROCELLULOSE, POLYESTERS I.E. ALKYD RESINS AND AMINO RESINS, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE MANUFACTURE OF COATINGS BAYER AG (DE) 1983-12-14 EP disclosed
EP-0056155-A1 Aqueous dispersions containing nitrocellulose, polyesters i.e. alkyd resins and amino resins, process for their preparation and their use for the manufacture of coatings BAYER AG (DE) 1982-07-21 EP disclosed