Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875016 | 0.81 | TDP1 (0.42) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL2001481 | 0.80 | TSHR (0.52) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL27213906 | 0.75 | CA12 (0.47) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL9874571 | 0.75 | KMT2A (0.44) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL9874142 | 0.74 | TSHR (0.42) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL2184188 | 0.73 | TSHR (0.48) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL1999063 | 0.73 | NR1H2 (0.52) | NPSR1TP53HTTTDP1TSHR | |
| SCHEMBL7813719 | 0.72 | TSHR (0.52) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9453805 | 0.72 | TSHR (0.72) | TP53TDP1TSHRALDH1A1MAPT | |
| SCHEMBL7014498 | 0.72 | KMT2A (0.44) | NPSR1TP53HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |