Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154293 | 0.96 | NFKB1 (0.51) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9766704 | 0.95 | RAB9A (0.50) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9156125 | 0.93 | SMN1; SMN2 (0.46) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9152788 | 0.92 | RAB9A (0.53) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9154167 | 0.91 | RAB9A (0.49) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9766608 | 0.91 | RAB9A (0.45) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9154233 | 0.90 | MAPT (0.51) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL10282267 | 0.89 | SMN1; SMN2 (0.49) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL9156732 | 0.88 | RAB9A (0.50) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL10721748 | 0.87 | RAB9A (0.51) | NFKB1L3MBTL1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |