Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877215 | 1.00 | ALDH1A1 (0.50) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL9875010 | 0.85 | CPB1 (0.47) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL9875439 | 0.84 | ALDH1A1 (0.51) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL9876032 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL4386438 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL3223998 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL25641905 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL8759021 | 0.80 | CPB1 (0.57) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL9875420 | 0.80 | CPB1 (0.57) | ALDH1A1GAATSHRCPB1EPHX1 | |
| SCHEMBL393163 | 0.80 | CPB1 (0.57) | ALDH1A1GAATSHRCPB1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043451-A | Bicyclo (2.2.1.) hept-exo-2-yl and bicyclo (2.2.2.) oct-endo-2-yl compounds | SHIONOGI & CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5043456-A | 6-oxa and thiabicyclo [3.1.0.] compounds | SHIONOGI & CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5041635-A | 5(Z)-7-(endo-3-benzenesulfonamidobicyclo[2.2.1]hept-exo-2-yl)-5-heptenoic acid, sodium salt | SHIONOGI & CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| US-4976891-A | Antithrombotic, antivasoconstricting, antibronchoconstricting | SHIONOGI & CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| US-4960909-A | ANTICOAGULANTS; VASODILATORS; BRONCHODILATOR AGENTS | SHIONOGI & CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4861913-A | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0226346-A1 | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |