Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377 | 0.86 | OGG1 (0.51) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| SCHEMBL29879678 | 0.86 | OGG1 (0.51) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| SCHEMBL18335371 | 0.86 | OGG1 (0.55) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| SCHEMBL29137024 | 0.86 | OGG1 (0.51) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| SCHEMBL337714 | 0.83 | CYP3A4 (0.63) | OGG1KMT2ABCHECYP3A4LMNA | |
| SCHEMBL15984587 | 0.83 | OGG1 (0.46) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| SCHEMBL15984596 | 0.83 | OGG1 (0.46) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| SCHEMBL31344417 | 0.82 | P2RX4 (0.48) | OGG1KMT2AL3MBTL1BCHEHPGD | |
| SCHEMBL20296798 | 0.82 | OGG1 (0.46) | OGG1KMT2AL3MBTL1TRPV1BCHE | |
| Ammonia Solution, Strong SCHEMBL28761898 | 0.81 | CYP3A4 (0.61) | OGG1KMT2ABCHECYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049694-A | Cardiovascular disorders | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-09-17 | — | — | US | disclosed |
| EP-0359335-A2 | Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance | CEDONA PHARMACEUTICALS B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |