Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28761898 | 0.98 | CYP3A4 (0.61) | CYP3A4LMNAACHEOGG1MEN1 | |
| SCHEMBL9671217 | 0.86 | RXRA (0.50) | CYP3A4LMNAOGG1MEN1KMT2A | |
| SCHEMBL17028900 | 0.85 | LMNA (0.76) | CYP3A4LMNAACHEMEN1KMT2A | |
| SCHEMBL249305 | 0.85 | LMNA (0.76) | CYP3A4LMNAACHEMEN1KMT2A | |
| SCHEMBL5790568 | 0.85 | OGG1 (0.47) | CYP3A4LMNAACHEOGG1MEN1 | |
| SCHEMBL27637477 | 0.84 | LMNA (0.47) | CYP3A4LMNAACHEMEN1KMT2A | |
| SCHEMBL217700 | 0.83 | WDR5 (0.46) | CYP3A4LMNAOGG1KMT2ABCHE | |
| SCHEMBL5916715 | 0.83 | BCHE (0.51) | LMNAOGG1MEN1KMT2ABCHE | |
| SCHEMBL7932475 | 0.83 | BCHE (0.51) | LMNAOGG1MEN1KMT2ABCHE | |
| SCHEMBL9875360 | 0.83 | OGG1 (0.54) | CYP3A4LMNAOGG1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368226-B | Hydroxy aryl ketone and preparation method thereof | 中国石油化工股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-115368226-A | Hydroxy arone and preparation method thereof | 中国石油化工股份有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-108440299-A | A method of preparing 4- nitro benzophenone class compounds | 长沙理工大学 | 2018-08-24 | — | — | CN | claimed |
| CN-107417509-A | A kind of preparation method of phenylacetic acid compound | 上海康鹏科技有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-107250102-A | Method for producing benzidine from azobenzene by ruthenium catalysis | 拜耳作物科学股份公司 | 2017-10-13 | — | — | CN | claimed |
| CN-104447581-A | Method for synthesizing N-heterocyclic compound | UNIV HUNAN | 2015-03-25 | — | — | CN | claimed |
| CN-103105391-A | Novel mercapto color developing agent, preparation method and application thereof | UNIV CHONGQING MEDICAL | 2013-05-15 | — | — | CN | claimed |
| CN-103058931-A | Four 2-(3', 5'-dihalo-benzyl) benzimidazole type novel compounds and preparation method thereof | GUANGDONG TONESET SCIENCE & TECHNOLOGY CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-101538542-B | Pseudomonad esterase and application in preparing optical pure mandel and derivative thereof | UNIV EAST CHINA SCIENCE & TECH | 2010-12-29 | — | — | CN | claimed |
| CN-120121751-A | Method for detecting chlorophenols in waste gas and application thereof | 华电莱州发电有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119528934-A | 2-Pyridothiophene compound, preparation method, application and antitubercular drug thereof | 桂林医学院 | 2025-02-28 | — | — | CN | disclosed |
| US-20240300892-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2024-09-12 | — | — | US | disclosed |
| CN-114984003-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-118302414-A | Oxazole, oxadiazole and indole derivatives useful for inhibiting USP28 | 卡莫特医疗有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-0227932-A1 | Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-07-08 | — | — | EP | disclosed |
| EP-0192535-A1 | Alpha-[oxo-2-hexahydro-2,4,5,6,7a-thieno(3,2-c)pyridyl-5]phenyl-acetic-acid derivatives, process for their preparation and their therapeutical use | SANOFI (FR) | 1986-08-27 | — | — | EP | disclosed |
| US-4091107-A | RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4055597-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300892-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | MDM2, TP53, CDKN1A | CYP3A4 3110/4885LMNA 2556/4885ACHE 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.