Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875369 | 1.00 | DRD2 (0.35) | DRD2SIGMAR1KMT2AMEN1RAB9A | |
| SCHEMBL9502372 | 0.84 | TSHR (0.35) | ALOX12 | |
| SCHEMBL9502380 | 0.84 | TSHR (0.35) | ALOX12 | |
| SCHEMBL8215476 | 0.72 | KMT2A (0.39) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL466883 | 0.72 | KMT2A (0.39) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL467154 | 0.71 | DRD4 (0.40) | KMT2AKDM4EALDH1A1LMNABLM | |
| Oxalic Acid SCHEMBL467153 | 0.71 | DRD4 (0.40) | KMT2AKDM4EALDH1A1LMNABLM | |
| Hydrochloric Acid SCHEMBL466882 | 0.71 | KMT2A (0.40) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3966062 | 0.69 | CTBP2 (0.56) | KMT2AMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL7697321 | 0.67 | MAOA (0.51) | DRD2SIGMAR1KMT2AMEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073561-A | N-substituted-pyridinyl oximes | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4929734-A | ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |