Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682320 | 0.91 | MEN1 (0.57) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10607926 | 0.85 | KDM4E (0.72) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10674894 | 0.82 | GAA (0.56) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10670596 | 0.80 | KDM4E (0.69) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10673389 | 0.80 | MEN1 (0.49) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL9875417 | 0.79 | MEN1 (0.50) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL9874474 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10681825 | 0.79 | GAA (0.65) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| Water SCHEMBL10680272 | 0.78 | MAPK1 (0.53) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10674862 | 0.77 | KDM4E (0.58) | MEN1KMT2AKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |