Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381137 | 0.80 | GABRP (0.39) | SMN1; SMN2L3MBTL1ALDH1A1HTTMEN1 | |
| SCHEMBL9875424 | 0.79 | MEN1 (0.52) | SMN1; SMN2L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL9874472 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL10678542 | 0.72 | KMT2A (0.67) | SMN1; SMN2L3MBTL1ALDH1A1NPSR1MAPT | |
| SCHEMBL9872674 | 0.70 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HTTNPSR1MAPT | |
| SCHEMBL7212190 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL9873674 | 0.69 | KMT2A (0.42) | SMN1; SMN2ALDH1A1HTTNPSR1MAPT | |
| SCHEMBL10682320 | 0.68 | MEN1 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL7496148 | 0.68 | CYP1A2 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1HTTMAPT | |
| Water SCHEMBL10680272 | 0.67 | MAPK1 (0.53) | SMN1; SMN2L3MBTL1ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |