Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875424 | 0.79 | MEN1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9874472 | 0.78 | SMN1; SMN2 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9874612 | 0.74 | MEN1 (0.62) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9875561 | 0.73 | MEN1 (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10675902 | 0.72 | MEN1 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9175047 | 0.71 | MEN1 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10682320 | 0.69 | MEN1 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9874916 | 0.68 | SMN1; SMN2 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL15190928 | 0.67 | KMT2A (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9875419 | 0.67 | LMNA (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |