Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 5/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725857 | 0.90 | CSF1R (0.47) | LMNAMAPTPDE4BCSF1RNR4A2 | |
| SCHEMBL2721434 | 0.85 | LMNA (0.58) | LMNAMAPTMEN1KMT2AMAPK10 | |
| SCHEMBL9872120 | 0.85 | LMNA (0.58) | LMNAMAPTNR4A2NUDT1MEN1 | |
| SCHEMBL2479384 | 0.84 | LMNA (0.42) | LMNAPDE4BPIK3CAPIK3CBMTOR | |
| SCHEMBL3866828 | 0.84 | CSF1R (0.46) | LMNAPDE4BCSF1RSLC2A1 | |
| SCHEMBL2725311 | 0.84 | HTT (0.49) | LMNAPDE4BCSF1RKMT2ASLC2A1 | |
| SCHEMBL2718832 | 0.84 | LMNA (0.56) | LMNAMAPTNR4A2NUDT1MEN1 | |
| Hydrochloric Acid SCHEMBL9872122 | 0.84 | LMNA (0.60) | LMNAMAPTMEN1KMT2AMAPK10 | |
| SCHEMBL2706557 | 0.83 | KMT2A (0.47) | LMNAMAPTPDE4BATMCSF1R | |
| SCHEMBL4627675 | 0.83 | SLC2A1 (0.48) | LMNAPDE4BPIK3CAPIK3CBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |