Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375614 | 0.78 | PDE4A (0.52) | EPHX2DRD2KMT2ALMNA | |
| SCHEMBL30047267 | 0.78 | PDE4A (0.52) | EPHX2DRD2KMT2ALMNA | |
| SCHEMBL30468602 | 0.78 | PDE4A (0.52) | EPHX2DRD2KMT2ALMNA | |
| SCHEMBL3375618 | 0.78 | PDE4A (0.52) | EPHX2DRD2KMT2ALMNA | |
| SCHEMBL9875528 | 0.77 | TAOK1 (0.44) | NFKB1NFKB2RELAL3MBTL1HTR2C | |
| SCHEMBL11305981 | 0.77 | XIAP (0.44) | KMT2AXIAPLMNAHTR2CSLC6A3 | |
| SCHEMBL5814321 | 0.76 | ALDH1A1 (0.49) | GAA | |
| SCHEMBL13603823 | 0.76 | DRD2 (0.42) | EPHX2DRD2KMT2AL3MBTL1XIAP | |
| SCHEMBL29551628 | 0.76 | HTT (0.59) | KMT2ALMNA | |
| SCHEMBL5714269 | 0.76 | HTT (0.59) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041673-A | Aminopeptidase inhibitors, immunomodulators, analgesics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |