Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.72 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879636 | 0.92 | SIGMAR1 (0.74) | SIGMAR1DRD2HTR7PPARGPPARA | |
| SCHEMBL9872889 | 0.90 | SIGMAR1 (0.59) | SIGMAR1DRD2HTR7PPARGPPARA | |
| SCHEMBL4587598 | 0.88 | SIGMAR1 (0.56) | SIGMAR1DRD2HTR7ABCB11TP53 | |
| Hydrochloric Acid SCHEMBL4589780 | 0.87 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR7ABCB11TP53 | |
| SCHEMBL10974420 | 0.84 | PPARG (0.55) | SIGMAR1HTR7KDM4EPPARGPPARA | |
| Hydrochloric Acid SCHEMBL10734491 | 0.83 | PPARG (0.54) | SIGMAR1HTR7KDM4EPPARGPPARA | |
| SCHEMBL4589148 | 0.82 | SIGMAR1 (0.48) | SIGMAR1DRD2HTR7KDM4EPPARG | |
| SCHEMBL4588826 | 0.81 | SIGMAR1 (0.47) | SIGMAR1DRD2HTR7KDM4EPPARG | |
| SCHEMBL4587710 | 0.81 | SIGMAR1 (0.52) | SIGMAR1HTR7KDM4EPPARGPPARA | |
| Hydrochloric Acid SCHEMBL4588524 | 0.81 | SIGMAR1 (0.47) | SIGMAR1DRD2HTR7KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |