Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.74 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875807 | 0.92 | SIGMAR1 (0.72) | SIGMAR1HTR7PPARGPPARADRD2 | |
| SCHEMBL9872889 | 0.90 | SIGMAR1 (0.59) | SIGMAR1HTR7PPARGPPARADRD2 | |
| SCHEMBL10974420 | 0.86 | PPARG (0.55) | SIGMAR1HTR7PPARGPPARAKCNA3 | |
| SCHEMBL4587710 | 0.85 | SIGMAR1 (0.52) | SIGMAR1HTR7PPARGPPARA | |
| Hydrochloric Acid SCHEMBL10734491 | 0.85 | PPARG (0.54) | SIGMAR1HTR7PPARGPPARAKCNA3 | |
| Hydrochloric Acid SCHEMBL4588328 | 0.84 | SIGMAR1 (0.51) | SIGMAR1HTR7PPARGPPARA | |
| SCHEMBL4589148 | 0.82 | SIGMAR1 (0.48) | SIGMAR1HTR7PPARGPPARADRD2 | |
| SCHEMBL4589087 | 0.82 | PPARG (0.50) | SIGMAR1HTR7PPARGPPARA | |
| SCHEMBL9501239 | 0.81 | SIGMAR1 (0.55) | SIGMAR1HTR7PPARGPPARAKCNA3 | |
| SCHEMBL6653223 | 0.81 | PPARG (0.51) | SIGMAR1HTR7PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |