SCHEMBL9876027

SCHEMBL9876027

Cc1c(Br)cc(F)c(F)c1Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16815600 0.78 CYP3A4 (0.33)
SCHEMBL4060447 0.78 KDM1A (0.31)
SCHEMBL29006241 0.78 CA12 (0.31)
SCHEMBL30434373 0.78 CA12 (0.31)
SCHEMBL334330 0.78 KDM1A (0.31)
SCHEMBL27850940 0.76 POLB (0.32) POLB
SCHEMBL16815606 0.75 CA2 (0.36) POLB
SCHEMBL31393240 0.74 PRKDC (0.32)
SCHEMBL15497511 0.73 HDAC1 (0.35)
SCHEMBL8526910 0.73 CA12 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990657-A From an aromatic halide without a phase transfer agent RHONE-POULENC CHIMIE (FR) 1991-02-05 US disclosed
EP-0255794-A1 Process for preparing an aromatic acid RHONE-POULENC CHIMIE (FR) 1988-02-10 EP disclosed