⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876553 | 0.75 | — | — | |
| SCHEMBL9876264 | 0.72 | GAA (0.38) | — | |
| SCHEMBL335305 | 0.71 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL9738264 | 0.71 | — | — | |
| SCHEMBL29364216 | 0.71 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL2310300 | 0.70 | MKNK1 (0.42) | — | |
| SCHEMBL1463944 | 0.70 | MKNK1 (0.42) | — | |
| SCHEMBL5518273 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL23864829 | 0.67 | KDM4E (0.35) | — | |
| SCHEMBL29526925 | 0.67 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049561-A | Anthelmintic acylhydrazones, method of use and compositions | THE UPJOHN COMPANY (US) | 1991-09-17 | — | — | US | claimed |
| EP-0370065-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1990-05-30 | — | — | EP | claimed |
| WO-1989000992-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1989-02-09 | — | — | WO | claimed |