Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265414 | 0.86 | HTR2C (0.47) | HTR2CHTR2BCA12CA9DRD2 | |
| SCHEMBL30523681 | 0.75 | CA12 (0.46) | CA12CA9ABCB1 | |
| SCHEMBL506743 | 0.75 | CA12 (0.46) | CA12CA9ABCB1 | |
| SCHEMBL1115308 | 0.73 | HTR2C (0.70) | HTR2CHTR2B | |
| SCHEMBL9765461 | 0.72 | CA12 (0.43) | CA12CA9ABCB1 | |
| SCHEMBL27364433 | 0.70 | HTR2C (0.33) | HTR2CHTR2B | |
| SCHEMBL8534981 | 0.69 | CA12 (0.40) | CA12CA9ABCB1 | |
| SCHEMBL6980284 | 0.68 | CA12 (0.40) | CA12CA9ABCB1 | |
| SCHEMBL9206139 | 0.68 | CA12 (0.40) | CA12CA9ABCB1 | |
| SCHEMBL9736524 | 0.68 | PTGS1 (0.46) | CA12CA9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |