Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876290 | 0.94 | REN (0.46) | RENCCR1 | |
| SCHEMBL9874799 | 0.93 | REN (0.49) | REN | |
| SCHEMBL10630729 | 0.93 | REN (0.46) | REN | |
| SCHEMBL9876391 | 0.93 | REN (0.43) | RENCCR1 | |
| SCHEMBL9876376 | 0.91 | REN (0.45) | REN | |
| SCHEMBL9876329 | 0.91 | REN (0.46) | REN | |
| SCHEMBL9876085 | 0.90 | REN (0.45) | REN | |
| SCHEMBL10767582 | 0.85 | REN (0.40) | RENCCR1 | |
| SCHEMBL9876262 | 0.83 | REN (0.45) | REN | |
| SCHEMBL10763181 | 0.81 | REN (0.64) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992562-A | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4729985-A | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0212903-A2 | Polypeptide derivatives containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1987-03-04 | — | — | EP | disclosed |