Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 11/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742155 | 0.68 | KCNA5 (0.40) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL9876565 | 0.66 | KDM4E (0.59) | KCNE1KCNQ1KDM4EABCB1CYP3A4 | |
| SCHEMBL9876570 | 0.66 | KDM4E (0.59) | KCNE1KCNQ1KDM4EABCB1CYP3A4 | |
| SCHEMBL9876573 | 0.66 | KDM4E (0.59) | KCNE1KCNQ1KDM4EABCB1CYP3A4 | |
| SCHEMBL27317744 | 0.65 | KCNE1 (0.55) | KCNE1KCNQ1KDM4E | |
| SCHEMBL9876365 | 0.64 | KDM4E (0.56) | KCNE1KCNQ1KDM4EABCB1CYP3A4 | |
| SCHEMBL9876369 | 0.64 | KDM4E (0.56) | KCNE1KCNQ1KDM4EABCB1CYP3A4 | |
| SCHEMBL9353579 | 0.64 | KCNE1 (0.46) | KCNE1KCNQ1KDM4E | |
| SCHEMBL5913614 | 0.63 | ALDH1A1 (0.63) | — | |
| SCHEMBL9443567 | 0.63 | ABCB1 (0.41) | KCNE1KCNQ1KDM4EABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |