Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214695 | 0.60 | TDP1 (0.64) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL20135556 | 0.59 | PDE4B (0.53) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27261595 | 0.59 | TDP1 (0.62) | MAPTMEN1HPGDKMT2A | |
| SCHEMBL14013174 | 0.59 | L3MBTL1 (0.52) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14398795 | 0.58 | MEN1 (0.35) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL11563040 | 0.58 | GSK3B (0.50) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL30552434 | 0.58 | PDE4B (0.70) | ALDH1A1MAPTKMT2A | |
| SCHEMBL1392323 | 0.58 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL1682671 | 0.57 | — | — | |
| SCHEMBL228309 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073561-A | N-substituted-pyridinyl oximes | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4929734-A | ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4798841-A | COGNITION ACTIVATORS, ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1989-01-17 | — | — | US | disclosed |
| EP-0291673-A1 | Tetrahydropyridine oximes, a process for their preparation and use thereof as cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |
| US-4710508-A | ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1987-12-01 | — | — | US | disclosed |