SCHEMBL9876503

SCHEMBL9876503

ClC(Cl)c1cccc2cccnc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.55
COPS5 Q92905 1/20 0.55
KDM4E B2RXH2 4/20 0.54
LMNA P02545 3/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
CCR1 P32246 2/20 0.54
CCR8 P51685 2/20 0.54
CYP3A4 P08684 2/20 0.54
MAPT P10636 2/20 0.54
ALOX15 P16050 2/20 0.54
HTT P42858 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
THPO P40225 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17541536 0.84 PSMD14 (0.52) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL28220687 0.84 PSMD14 (0.52) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL28037486 0.84 PSMD14 (0.52) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL27536022 0.81 PSMD14 (0.48) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL30667194 0.79 PSMD14 (0.55) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL16084043 0.79 MMP2 (0.55) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL31490195 0.79 PSMD14 (0.55) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL84502 0.79 PSMD14 (0.55) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL28012735 0.79 PSMD14 (0.55) PSMD14COPS5KDM4ELMNAMMP2
SCHEMBL7381843 0.78 PSMD14 (0.53) PSMD14COPS5KDM4ELMNAMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102796042-A Method for catalytically oxidizing quinclorac JIANGSU LULILAI CO LTD 2012-11-28 CN claimed
CN-101851197-B Method for synthesizing and refining quinclorac JIANGSU LULILAI CO LTD 2011-03-23 CN claimed
CN-101851197-A Method for synthesizing and refining quinclorac JIANGSU LULILAI CO LTD 2010-10-06 CN claimed
CN-109173602-A A kind of circulation utilization method of the nitrous oxides exhaust gas generated in dichloro quinolinic acid synthesis 华东理工大学 2019-01-11 CN disclosed
CN-107868047-A Method for preparing quinclorac through catalytic oxidation 南京工业大学 2018-04-03 CN disclosed
CN-103420909-B A kind of liquid phase catalytic oxidation is prepared the method for dichloro quinolinic acid SINOCHEM CORPORATION (CN) 2016-05-18 CN disclosed
CN-102942524-B Preparation method of quinoline derivative BEIJING VAGEAN TECHNOLOGY CO LTD 2014-12-31 CN disclosed
CN-103420909-A Liquid-phase catalytic oxidation quinclorac preparation method SINOCHEM CORP 2013-12-04 CN disclosed
CN-102942524-A Preparation method of quinoline derivative BEIJING VAGEAN SCIENCE & TECHNOLOGY CO LTD 2013-02-27 CN disclosed
CN-102796042-A Method for catalytically oxidizing quinclorac JIANGSU LULILAI CO LTD 2012-11-28 CN disclosed
CN-101851197-B Method for synthesizing and refining quinclorac JIANGSU LULILAI CO LTD 2011-03-23 CN disclosed
CN-101851197-A Method for synthesizing and refining quinclorac JIANGSU LULILAI CO LTD 2010-10-06 CN disclosed
US-5062879-A 8-AZOLYLMETHYLQUINOLINES AND HERBICIDAL USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1991-11-05 US disclosed
EP-0399394-A1 8-Azolylmethylquinolines BASF Aktiengesellschaft (DE) 1990-11-28 EP disclosed