Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.46 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.46 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.41 |
| ▸ | MAOA | P21397 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158721 | 0.84 | MEN1 (0.58) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL13352408 | 0.81 | MEN1 (0.60) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL8608558 | 0.80 | MEN1 (0.69) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL10612207 | 0.80 | LPL (0.39) | MEN1CYP2C19KMT2ABRD4MAPK1 | |
| SCHEMBL10612205 | 0.80 | LPL (0.39) | MEN1CYP2C19KMT2ABRD4MAPK1 | |
| SCHEMBL10612728 | 0.78 | ELANE (0.39) | MEN1CYP2C19KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10612731 | 0.78 | ELANE (0.39) | MEN1CYP2C19KMT2AMAPK1ALDH1A1 | |
| SCHEMBL4812907 | 0.77 | MEN1 (0.55) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL9619377 | 0.76 | MEN1 (0.53) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL16359538 | 0.76 | MAPK1 (0.55) | MEN1CYP2C19KMT2AKCNA4KCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |