Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864097 | 0.98 | LMNA (0.40) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9864186 | 0.98 | LMNA (0.40) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9863698 | 0.98 | LMNA (0.40) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL4983254 | 0.92 | PRMT5 (0.45) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9863774 | 0.90 | TDP1 (0.47) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9876569 | 0.89 | TDP1 (0.46) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9863576 | 0.89 | TDP1 (0.46) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9863994 | 0.89 | TDP1 (0.46) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9863593 | 0.87 | TDP1 (0.45) | LMNAPOLBHSD17B10PRMT5WDR77 | |
| SCHEMBL9863801 | 0.81 | TDP1 (0.44) | LMNAPOLBPRMT5WDR77ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015524-A | Lens sheet | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| EP-0376254-A2 | Lens sheet | MITSUBISHI RAYON CO., LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |