Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.65 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.65 |
| ▸ | SAT1 | P21673 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780243 | 0.98 | GNAI3 (0.68) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL11922711 | 0.96 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL8515191 | 0.94 | GNAI3 (0.62) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL27382583 | 0.94 | GNAI3 (0.62) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL24062846 | 0.93 | SAT1 (0.57) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL8603624 | 0.92 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL28997937 | 0.92 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL1932361 | 0.92 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL11576183 | 0.92 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL28709614 | 0.92 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | disclosed |
| US-4925879-A | ANTIDEPRESSANTS | BOOTS COMPANY, PLC (GB) | 1990-05-15 | — | — | US | disclosed |