Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.62 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.62 |
| ▸ | SAT1 | P21673 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382583 | 1.00 | GNAI3 (0.62) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL8603624 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL28709614 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL11576183 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL28997937 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL11922711 | 0.98 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3966575 | 0.96 | GNAI3 (0.69) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL9876649 | 0.94 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL842526 | 0.94 | SAT1 (0.55) | GNAI3GNAO1GNAI1SAT1CYP1A2 | |
| SCHEMBL18780243 | 0.92 | GNAI3 (0.68) | GNAI3GNAO1GNAI1SAT1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236965-B2 | Benzimidazole derivatives and their use as a medicament | IPSEN PHARMA S.A.S. (FR) | 2012-08-07 | — | — | US | disclosed |
| US-20090170922-A1 | Benzimidazole derivatives and their use as a medicament | SOCIETE DE CONSEILS DE RECHERECHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2009-07-02 | — | — | US | disclosed |
| US-7495110-B2 | Benzimidazole derivatives and their use as GnRH antagonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2009-02-24 | — | — | US | disclosed |
| WO-1999029705-A9 | SIALYL LEWIS X AND SIALYL LEWIS A GLYCOMIMETICS | GLYCOMED INC (US) | 1999-11-11 | — | — | WO | disclosed |
| WO-1999029705-A2 | SIALYL LEWIS X AND SIALYL LEWIS A GLYCOMIMETICS | GLYCOMED INCORPORATED (US) | 1999-06-17 | — | — | WO | disclosed |
| US-5733931-A | ANTICHOLESTEROL AGENTS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170922-A1 | Benzimidazole derivatives and their use as a medicament | GNRHR, FSHR, KISS1R | GNAI3 549/4885GNAO1 859/4885GNAI1 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.