Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378731 | 0.81 | CYP3A4 (0.57) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL9795408 | 0.77 | CYP19A1 (0.53) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL11396775 | 0.77 | CYP3A4 (0.44) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL10419923 | 0.77 | SMN1; SMN2 (0.47) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL11563987 | 0.77 | CYP19A1 (0.47) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL6227295 | 0.76 | CYP19A1 (0.51) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL10709515 | 0.76 | CYP19A1 (0.55) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL6203481 | 0.76 | CYP19A1 (0.46) | KMT2AHSP90AA1MEN1POLBCYP19A1 | |
| SCHEMBL11559138 | 0.76 | KMT2A (0.48) | KMT2AHSP90AA1MEN1CYP19A1CYP3A4 | |
| SCHEMBL11196779 | 0.75 | CYP19A1 (0.58) | KMT2AHSP90AA1MEN1POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010208-A | Novel alkylcycloalkyl triazolylmethyl ketones as fungicide intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| US-4921967-A | Novel alkylcycloalkyl triazolylmethyl ketones as fungicide intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| EP-0081675-B1 | ALKYLCYCLOALKYL-TRIAZOLYLMETHYL KETONES AND PROCESS FOR PREPARING THEM | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0080102-B1 | CYCLOALKYL-(ALPHA-TRIAZOLYL-BETA-HYDROXY) KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND PLANT GROWTH REGULATORS | BAYER AG (DE) | 1986-05-28 | — | — | EP | disclosed |
| US-4530715-A | Cycloalkyl (α-triazolyl-β-hydroxy)-ketones as fungicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-23 | — | — | US | disclosed |
| EP-0081675-A1 | Alkylcycloalkyl-triazolylmethyl ketones and process for preparing them | BAYER AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0080102-A1 | Cycloalkyl-(alpha-triazolyl-beta-hydroxy) ketones, process for their preparation and their use as fungicides and plant growth regulators | BAYER AG (DE) | 1983-06-01 | — | — | EP | disclosed |