Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.49 |
| ▸ | CDK2 | P24941 | 7/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876766 | 0.94 | PTGER1 (0.53) | PTGER1CCNA2CDK2CDK1CDK4 | |
| SCHEMBL9877081 | 0.88 | CCNA2 (0.49) | PTGER1CCNA2CDK2NPSR1MAPT | |
| SCHEMBL9876850 | 0.88 | MAPT (0.47) | PTGER1CCNA2CDK2GAANPSR1 | |
| SCHEMBL9876695 | 0.88 | CCNA2 (0.49) | PTGER1CCNA2CDK2GAANPSR1 | |
| SCHEMBL9876681 | 0.88 | CCNA2 (0.49) | PTGER1CCNA2CDK2GAANPSR1 | |
| SCHEMBL9876890 | 0.85 | PTGER1 (0.50) | PTGER1CCNA2CDK2CDK1CDK4 | |
| SCHEMBL9236865 | 0.81 | PTGER1 (0.49) | PTGER1CCNA2CDK2MEN1KMT2A | |
| SCHEMBL9876637 | 0.80 | PTGER1 (0.50) | PTGER1CCNA2CDK2CDK1CDK4 | |
| SCHEMBL10590202 | 0.80 | PTGER1 (0.48) | PTGER1CCNA2CDK2CDK1CDK4 | |
| SCHEMBL19465579 | 0.79 | CCNA2 (0.53) | CCNA2CDK2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |