Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876686 | 0.88 | PTGER1 (0.50) | CCNA2CDK2NPSR1GAASRC | |
| SCHEMBL9876766 | 0.88 | PTGER1 (0.53) | CCNA2CDK2GAASRCESR2 | |
| SCHEMBL9877081 | 0.87 | CCNA2 (0.49) | CCNA2CDK2NPSR1ESR2PTGER1 | |
| SCHEMBL9876681 | 0.87 | CCNA2 (0.49) | CCNA2CDK2NPSR1GAAPTGER1 | |
| SCHEMBL9876798 | 0.86 | CDK2 (0.51) | CCNA2CDK2NPSR1GAASRC | |
| SCHEMBL9876850 | 0.82 | MAPT (0.47) | CCNA2CDK2NPSR1GAAPTGER1 | |
| SCHEMBL9876899 | 0.77 | CXCR1 (0.45) | CCNA2CDK2NPSR1GAAMAPT | |
| SCHEMBL9876833 | 0.75 | NAMPT (0.54) | PTGER1HPGDESR1 | |
| SCHEMBL10484556 | 0.74 | PTGER1 (0.41) | CCNA2CDK2NPSR1GAAPTGER1 | |
| SCHEMBL9876637 | 0.74 | PTGER1 (0.50) | CCNA2CDK2GAASRCPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |