Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876890 | 0.92 | PTGER1 (0.50) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9876798 | 0.91 | CDK2 (0.51) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9876720 | 0.91 | CDK2 (0.46) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9876686 | 0.88 | PTGER1 (0.50) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9877081 | 0.84 | CCNA2 (0.49) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9876766 | 0.82 | PTGER1 (0.53) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9876681 | 0.82 | CCNA2 (0.49) | MAPTMEN1KMT2AMAPK1PTGER1 | |
| SCHEMBL9876695 | 0.82 | CCNA2 (0.49) | MAPTKMT2AMAPK1PTGER1CDK2 | |
| SCHEMBL9876833 | 0.75 | NAMPT (0.54) | PTGER1ALDH1A1HPGDSMN1; SMN2ESR1 | |
| SCHEMBL9876903 | 0.74 | CCNA2 (0.53) | MAPTMAPK1PTGER1CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |