Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | BMP4 | P12644 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9238551 | 0.92 | LSS (0.43) | TNK2PSMB5PSMB1CCNA2CDK2 | |
| Fumaric Acid SCHEMBL9238560 | 0.92 | LSS (0.43) | TNK2PSMB5PSMB1CCNA2CDK2 | |
| SCHEMBL10593084 | 0.91 | TNK2 (0.46) | TNK2PSMB5PSMB1PTPN1CCNA2 | |
| SCHEMBL9876756 | 0.87 | LSS (0.43) | PSMB5PSMB1PTPN1CCNA2CDK2 | |
| Fumaric Acid SCHEMBL9235197 | 0.84 | BCHE (0.44) | TNK2PSMB5PSMB1MCHR1CYP1A2 | |
| Maleic Acid SCHEMBL9235189 | 0.84 | BCHE (0.44) | TNK2PSMB5PSMB1MCHR1CYP1A2 | |
| SCHEMBL9876810 | 0.80 | TNK2 (0.46) | TNK2PSMB5PSMB1PTPN1CCNA2 | |
| Maleic Acid SCHEMBL9230881 | 0.80 | LSS (0.47) | PSMB5PSMB1CCNA2CDK2LSS | |
| Fumaric Acid SCHEMBL9230885 | 0.80 | LSS (0.47) | PSMB5PSMB1CCNA2CDK2LSS | |
| SCHEMBL9876652 | 0.78 | LSS (0.44) | PSMB5PSMB1PTPN1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |