Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9236957 | 0.92 | PSMB5 (0.43) | TNK2PSMB5CCNA2CDK2LTA4H | |
| Maleic Acid SCHEMBL9236952 | 0.92 | PSMB5 (0.43) | TNK2PSMB5CCNA2CDK2LTA4H | |
| SCHEMBL9877072 | 0.91 | GSK3B (0.43) | TNK2PSMB5LTA4HFGFR1SRC | |
| SCHEMBL9876882 | 0.90 | LSS (0.52) | PSMB5CCNA2CDK2LSSFGFR1 | |
| SCHEMBL9234476 | 0.89 | TNK2 (0.44) | TNK2CCNA2CDK2LTA4HFGFR1 | |
| Fumaric Acid SCHEMBL9237418 | 0.88 | PTGER1 (0.43) | TNK2PSMB5CCNA2CDK2LTA4H | |
| Maleic Acid SCHEMBL9237412 | 0.88 | PTGER1 (0.43) | TNK2PSMB5CCNA2CDK2LTA4H | |
| Maleic Acid SCHEMBL9230995 | 0.87 | LSS (0.45) | PSMB5CCNA2CDK2LSSPSMB1 | |
| Fumaric Acid SCHEMBL9231005 | 0.87 | LSS (0.45) | PSMB5CCNA2CDK2LSSPSMB1 | |
| SCHEMBL9876652 | 0.86 | LSS (0.44) | PSMB5CCNA2CDK2LSSPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |