Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9230885 | 0.92 | LSS (0.47) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Maleic Acid SCHEMBL9230881 | 0.92 | LSS (0.47) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876652 | 0.91 | LSS (0.44) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876882 | 0.91 | LSS (0.52) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876899 | 0.90 | CXCR1 (0.45) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876835 | 0.87 | TNK2 (0.42) | LSSCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9876909 | 0.87 | LSS (0.44) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876810 | 0.85 | TNK2 (0.46) | LSSCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9235049 | 0.84 | LSS (0.42) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Maleic Acid SCHEMBL9230995 | 0.84 | LSS (0.45) | LSSCCNA2CDK2KDRTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |