Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12301081 | 0.91 | KMT2A (0.70) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL26454870 | 0.85 | ALDH1A1 (0.89) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL26454875 | 0.84 | ALDH1A1 (0.75) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL2320640 | 0.83 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL2318728 | 0.83 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL7638824 | 0.83 | MEN1 (1.00) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL6606481 | 0.80 | KMT2A (0.76) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL31666083 | 0.79 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL26098455 | 0.79 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1MAPK1TP53 | |
| SCHEMBL6609886 | 0.78 | MEN1 (0.73) | KMT2AMEN1ALDH1A1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985430-A | ALZHEIMER*S DISEASE | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |