Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098455 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL31666079 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL26098464 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL12301081 | 0.88 | KMT2A (0.70) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL26454719 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL26100476 | 0.87 | TDP1 (0.56) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL31666080 | 0.87 | TDP1 (0.56) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL26454732 | 0.87 | MAPT (0.68) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL26099431 | 0.84 | MAPT (0.70) | ALDH1A1MAPK1TP53KMT2AMEN1 | |
| SCHEMBL26098359 | 0.81 | MAPT (0.60) | ALDH1A1MAPK1TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12370183-B2 | Compositions and methods for treating malaria | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12370183-B2 | Compositions and methods for treating malaria | G6PD, QDPR, FASN | ALDH1A1 1569/4885MAPK1 4097/4885TP53 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.