Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9236150 | 0.96 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP3A4MAPTHTT | |
| Fumaric Acid SCHEMBL9236146 | 0.96 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP3A4MAPTHTT | |
| SCHEMBL9876805 | 0.91 | LMNA (0.44) | MAPTSMN1; SMN2LMNAHPGDRXFP1 | |
| SCHEMBL9237439 | 0.88 | CYP1A2 (0.43) | CYP1A2CYP2D6CYP3A4MAPTHTT | |
| Fumaric Acid SCHEMBL9236944 | 0.87 | LMNA (0.41) | MAPTSMN1; SMN2LMNAHPGDRXFP1 | |
| Maleic Acid SCHEMBL9236940 | 0.87 | LMNA (0.41) | MAPTSMN1; SMN2LMNAHPGDRXFP1 | |
| SCHEMBL9236865 | 0.82 | PTGER1 (0.49) | HTTSMN1; SMN2LMNAHPGDMAPK1 | |
| SCHEMBL9235670 | 0.80 | MAPT (0.50) | MAPTSMN1; SMN2HPGDALDH1A1MAPK1 | |
| SCHEMBL10593084 | 0.79 | TNK2 (0.46) | CYP1A2CYP2D6MAPTHTTALDH1A1 | |
| Maleic Acid SCHEMBL9235189 | 0.79 | BCHE (0.44) | CYP1A2CYP2D6MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |