Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9236944 | 0.96 | LMNA (0.41) | LMNASMN1; SMN2HPGDROCK2ROCK1 | |
| Maleic Acid SCHEMBL9236940 | 0.96 | LMNA (0.41) | LMNASMN1; SMN2HPGDROCK2ROCK1 | |
| SCHEMBL9876904 | 0.91 | CYP1A2 (0.51) | LMNASMN1; SMN2HPGDRXFP1ALDH1A1 | |
| Fumaric Acid SCHEMBL9236150 | 0.87 | CYP1A2 (0.47) | LMNASMN1; SMN2HPGDRXFP1ALDH1A1 | |
| Fumaric Acid SCHEMBL9236146 | 0.87 | CYP1A2 (0.47) | LMNASMN1; SMN2HPGDRXFP1ALDH1A1 | |
| SCHEMBL9236865 | 0.83 | PTGER1 (0.49) | LMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL9876810 | 0.82 | TNK2 (0.46) | — | |
| Fumaric Acid SCHEMBL9236957 | 0.81 | PSMB5 (0.43) | SMN1; SMN2ALDH1A1 | |
| Maleic Acid SCHEMBL9236952 | 0.81 | PSMB5 (0.43) | SMN1; SMN2ALDH1A1 | |
| Maleic Acid SCHEMBL9230995 | 0.81 | LSS (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |