Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9234293 | 0.92 | CCNA2 (0.36) | CDK2CCNA2L3MBTL1POLBPSMB5 | |
| Fumaric Acid SCHEMBL9234296 | 0.92 | CCNA2 (0.36) | CDK2CCNA2L3MBTL1POLBPSMB5 | |
| SCHEMBL9877611 | 0.92 | CCNA2 (0.41) | CDK2CCNA2PSMB5PSMB1MEN1 | |
| SCHEMBL9236551 | 0.90 | GAA (0.35) | CDK2CCNA2TP53GAARXFP1 | |
| SCHEMBL9876768 | 0.87 | CCNA2 (0.40) | CDK2CCNA2L3MBTL1POLBTP53 | |
| SCHEMBL9238567 | 0.86 | MEN1 (0.35) | CDK2CCNA2L3MBTL1TP53PSMB5 | |
| SCHEMBL9235835 | 0.86 | TP53 (0.37) | CDK2CCNA2POLBTP53GAA | |
| Maleic Acid SCHEMBL9235074 | 0.85 | PTGER1 (0.41) | CDK2CCNA2PSMB5PSMB1MEN1 | |
| Fumaric Acid SCHEMBL9235079 | 0.85 | PTGER1 (0.41) | CDK2CCNA2PSMB5PSMB1MEN1 | |
| SCHEMBL9876652 | 0.83 | LSS (0.44) | CDK2CCNA2L3MBTL1PSMB5PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |