Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9235079 | 0.93 | PTGER1 (0.41) | CCNA2CDK2PTGER1MEN1KMT2A | |
| Maleic Acid SCHEMBL9235074 | 0.93 | PTGER1 (0.41) | CCNA2CDK2PTGER1MEN1KMT2A | |
| SCHEMBL9876954 | 0.92 | CDK2 (0.39) | CCNA2CDK2MEN1KMT2APSMB5 | |
| SCHEMBL9876520 | 0.90 | PTGER1 (0.38) | CCNA2CDK2PTGER1MEN1KMT2A | |
| Maleic Acid SCHEMBL9234293 | 0.87 | CCNA2 (0.36) | CCNA2CDK2PTGER1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9234296 | 0.87 | CCNA2 (0.36) | CCNA2CDK2PTGER1MEN1KMT2A | |
| SCHEMBL9238567 | 0.86 | MEN1 (0.35) | CCNA2CDK2PTGER1MEN1KMT2A | |
| SCHEMBL9236551 | 0.85 | GAA (0.35) | CCNA2CDK2MEN1KMT2APSMB5 | |
| Maleic Acid SCHEMBL9237812 | 0.84 | PTGER1 (0.40) | CCNA2CDK2PTGER1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9237819 | 0.84 | PTGER1 (0.40) | CCNA2CDK2PTGER1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |