Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876954 | 0.86 | CDK2 (0.39) | MEN1KMT2ACDK2CDK4L3MBTL1 | |
| SCHEMBL9877611 | 0.86 | CCNA2 (0.41) | MEN1KMT2APTGER1CDK2CDK4 | |
| SCHEMBL9235047 | 0.84 | LSS (0.46) | KDM4EALDH1A1 | |
| SCHEMBL9236551 | 0.84 | GAA (0.35) | MEN1KMT2ACDK2MAPTTP53 | |
| SCHEMBL9876520 | 0.80 | PTGER1 (0.38) | MEN1KMT2APTGER1CDK2MAPT | |
| Maleic Acid SCHEMBL9235074 | 0.80 | PTGER1 (0.41) | MEN1KMT2APTGER1CDK2PSMB5 | |
| Fumaric Acid SCHEMBL9235079 | 0.80 | PTGER1 (0.41) | MEN1KMT2APTGER1CDK2PSMB5 | |
| Maleic Acid SCHEMBL9234293 | 0.80 | CCNA2 (0.36) | MEN1KMT2APTGER1CDK2L3MBTL1 | |
| Fumaric Acid SCHEMBL9234296 | 0.80 | CCNA2 (0.36) | MEN1KMT2APTGER1CDK2L3MBTL1 | |
| SCHEMBL9876885 | 0.78 | CCNA2 (0.37) | MEN1KMT2ACDK2TP53CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641564-A1 | OPTICALLY ACTIVE CONDENSED PYRAZOLE COMPOUND FOR USE IN TREATING THROMBOCYTOPENIA AND ERYTHROPENIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |