Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876736 | 0.95 | GAA (0.49) | GAAMAPTPOLBNPSR1L3MBTL1 | |
| Maleic Acid SCHEMBL9236897 | 0.95 | GAA (0.46) | GAAMAPTPOLBNPSR1L3MBTL1 | |
| Fumaric Acid SCHEMBL9236902 | 0.95 | GAA (0.46) | GAAMAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL9876908 | 0.91 | ALDH1A1 (0.51) | GAAMAPTPOLBNPSR1L3MBTL1 | |
| Fumaric Acid SCHEMBL9236905 | 0.90 | GAA (0.47) | GAAMAPTPOLBNPSR1L3MBTL1 | |
| Maleic Acid SCHEMBL9236899 | 0.90 | GAA (0.47) | GAAMAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL9877732 | 0.89 | ALDH1A1 (0.53) | NPSR1ALDH1A1HPGDKDM4ELSS | |
| SCHEMBL9877123 | 0.89 | LSS (0.42) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL9876697 | 0.88 | LSS (0.43) | ALDH1A1HPGDKDM4ELSSLTA4H | |
| SCHEMBL9234584 | 0.88 | LSS (0.46) | ALDH1A1HPGDKDM4ELSSLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |