Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10591933 | 0.94 | LSS (0.41) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9234584 | 0.92 | LSS (0.46) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9877732 | 0.91 | ALDH1A1 (0.53) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9879836 | 0.89 | LSS (0.41) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9876979 | 0.88 | GAA (0.48) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9876682 | 0.87 | GSK3B (0.43) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9234490 | 0.86 | GSK3B (0.50) | LSSKDM4EALDH1A1GSK3BKDR | |
| SCHEMBL9876891 | 0.86 | LSS (0.44) | LSSKDM4EALDH1A1HPGDGSK3B | |
| Fumaric Acid SCHEMBL9237908 | 0.86 | ALDH1A1 (0.48) | LSSKDM4EALDH1A1HPGDGSK3B | |
| SCHEMBL9877130 | 0.86 | CACNA1H (0.46) | LSSKDM4EALDH1A1HPGDGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |