Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236247 | 0.88 | KAT2B (0.44) | GAAALDH1A1MAPTHPGDNAMPT | |
| SCHEMBL9876736 | 0.85 | GAA (0.49) | GAAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9876979 | 0.84 | GAA (0.48) | GAAKMT2AMEN1ALDH1A1POLB | |
| Fumaric Acid SCHEMBL9236905 | 0.80 | GAA (0.47) | GAAKMT2AMEN1ALDH1A1POLB | |
| Maleic Acid SCHEMBL9236899 | 0.80 | GAA (0.47) | GAAKMT2AMEN1ALDH1A1POLB | |
| Fumaric Acid SCHEMBL9236902 | 0.80 | GAA (0.46) | GAAKMT2AMEN1ALDH1A1POLB | |
| Maleic Acid SCHEMBL9236897 | 0.80 | GAA (0.46) | GAAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9235926 | 0.79 | GAA (0.47) | GAAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9235920 | 0.79 | GAA (0.47) | GAAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9877149 | 0.78 | NAMPT (0.53) | GAAHPGDNAMPTKAT2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |