Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9232273 | 0.91 | NAMPT (0.52) | NAMPTKAT2BHPGDCYP2C19KDM4E | |
| Fumaric Acid SCHEMBL9232280 | 0.91 | NAMPT (0.52) | NAMPTKAT2BHPGDCYP2C19KDM4E | |
| SCHEMBL9876892 | 0.82 | KAT2B (0.42) | KAT2BHPGDCYP2C19SCN9AKDM4E | |
| SCHEMBL9236247 | 0.82 | KAT2B (0.44) | NAMPTKAT2BHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9877191 | 0.79 | ADORA3 (0.41) | NAMPTKAT2BCYP2C19 | |
| SCHEMBL9876982 | 0.78 | GAA (0.48) | NAMPTKAT2BHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9236866 | 0.77 | CYP2C19 (0.43) | KAT2BCYP2C19SCN9AKDM4ESMN1; SMN2 | |
| SCHEMBL9235819 | 0.76 | KDM4E (0.47) | SCN9AKDM4E | |
| SCHEMBL9876833 | 0.74 | NAMPT (0.54) | NAMPTHPGDGRM5SMN1; SMN2 | |
| Fumaric Acid SCHEMBL9236129 | 0.73 | ADORA3 (0.42) | NAMPTKAT2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |