Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686433 | 0.89 | MAPT (0.56) | MAPTVCAM1EGFRHSD17B10TRPA1 | |
| SCHEMBL11442634 | 0.81 | MAPT (1.00) | MAPTVCAM1EGFRHSD17B10HTT | |
| SCHEMBL11442635 | 0.81 | MAPT (1.00) | MAPTVCAM1EGFRHSD17B10HTT | |
| SCHEMBL6684887 | 0.81 | EGFR (0.56) | MAPTEGFRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL21865015 | 0.81 | EGFR (0.60) | MAPTEGFRHSD17B10HTTKMT2A | |
| SCHEMBL11442336 | 0.80 | MAPT (0.60) | MAPTVCAM1HSD17B10HTTKMT2A | |
| SCHEMBL11442333 | 0.80 | MAPT (0.60) | MAPTVCAM1HSD17B10HTTKMT2A | |
| SCHEMBL29289213 | 0.76 | MAPT (0.55) | MAPTVCAM1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL29289216 | 0.76 | MAPT (0.55) | MAPTVCAM1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL16951936 | 0.76 | HSD17B10 (0.62) | MAPTVCAM1HSD17B10HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |
| US-4184871-A | A,B-UNSATURATED NITRILE SENSITIZER | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1980-01-22 | — | — | US | disclosed |