Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9237812 | 0.93 | PTGER1 (0.40) | PTGER1CCNA2CDK2SLC16A3SLC16A1 | |
| Fumaric Acid SCHEMBL9237819 | 0.93 | PTGER1 (0.40) | PTGER1CCNA2CDK2SLC16A3SLC16A1 | |
| SCHEMBL9876945 | 0.92 | CCNA2 (0.37) | CCNA2CDK2MEN1KMT2AHIF1A | |
| SCHEMBL9876885 | 0.92 | CCNA2 (0.37) | CCNA2CDK2MEN1KMT2AHIF1A | |
| SCHEMBL9877611 | 0.90 | CCNA2 (0.41) | PTGER1CCNA2CDK2MEN1KMT2A | |
| SCHEMBL9876523 | 0.88 | PTGER1 (0.39) | PTGER1CCNA2CDK2SLC16A3SLC16A1 | |
| SCHEMBL9236551 | 0.88 | GAA (0.35) | CCNA2CDK2MEN1KMT2ATSHR | |
| SCHEMBL9877014 | 0.87 | PTGER1 (0.41) | PTGER1CCNA2CDK2PDE4AKCNH2 | |
| SCHEMBL9877134 | 0.87 | TP53 (0.36) | PTGER1SLC16A3SLC16A1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9234660 | 0.86 | NPSR1 (0.38) | PTGER1CCNA2CDK2SLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | claimed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |