Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877863 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9878145 | 0.88 | LMNA (0.47) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9877447 | 0.88 | LMNA (0.47) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9877446 | 0.88 | LMNA (0.47) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9878143 | 0.88 | LMNA (0.47) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9877782 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9877780 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9878363 | 0.84 | ALDH1A1 (0.39) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9878369 | 0.84 | ALDH1A1 (0.39) | ALDH1A1LMNAPKMKDM4EMAPK1 | |
| SCHEMBL9877896 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAPKMKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385267-A2 | Pyridine derivatives, their preparation and their use as fungicides | CIBA-GEIGY AG (CH) | 1990-09-05 | — | — | EP | claimed |
| US-5036074-A | In agriculture and horticulture | CIBA-GEIGY CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0385267-A2 | Pyridine derivatives, their preparation and their use as fungicides | CIBA-GEIGY AG (CH) | 1990-09-05 | — | — | EP | disclosed |