Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878033 | 1.00 | FKBP1A (0.49) | FKBP1AHTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9878265 | 0.92 | HTR2C (0.48) | FKBP1AHTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9877415 | 0.92 | HTR2C (0.48) | FKBP1AHTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3268475 | 0.91 | FKBP1A (0.50) | FKBP1ATSHRCYP3A4ACEALOX15 | |
| SCHEMBL19042 | 0.91 | ACE (0.53) | HTR2CSMN1; SMN2NPC1RAB9ACYP3A4 | |
| SCHEMBL4796474 | 0.91 | ACE (0.51) | FKBP1AHTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4798767 | 0.89 | FKBP1A (0.49) | FKBP1AHTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4799717 | 0.89 | ACE (0.53) | HTR2CSMN1; SMN2NPC1RAB9ACYP3A4 | |
| SCHEMBL3843206 | 0.89 | ACE (0.53) | HTR2CSMN1; SMN2NPC1RAB9ACYP3A4 | |
| SCHEMBL4848858 | 0.89 | ACE (0.53) | HTR2CSMN1; SMN2NPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011940-A | Process for the preparation of bicyclic amino carboxylic acids, intermediates in this process, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |