Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878265 | 1.00 | HTR2C (0.48) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL4798767 | 0.98 | FKBP1A (0.49) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL9878033 | 0.92 | FKBP1A (0.49) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL9877388 | 0.92 | FKBP1A (0.49) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL19042 | 0.88 | ACE (0.53) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL4796474 | 0.87 | ACE (0.51) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL4798899 | 0.86 | ACE (0.48) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL4798929 | 0.86 | CYP3A4 (0.53) | CYP3A4KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4848858 | 0.85 | ACE (0.53) | HTR2CCYP3A4KMT2AACEMEN1 | |
| SCHEMBL4799717 | 0.85 | ACE (0.53) | HTR2CCYP3A4KMT2AACEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011940-A | Process for the preparation of bicyclic amino carboxylic acids, intermediates in this process, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |